Peripheral Vascular Disease dangerous for the heart

Peripheral Vascular Disease is a serious condition that often reveals itself through pain in the legs or other extremities. Often called Peripheral Artery Disease or Peripheral Arterial Disease (PAD), it is the result of arteriosclerosis or restricted blood flow caused by a buildup of plaque on the inner walls of the arteries. When the flow of blood is limited, limbs, the heart and brain are deprived of the oxygen. Additionally, muscle cells in the wall of the artery overgrow and fat and calcium build up within these irregular spaces. Bleeding into the artery wall can also occur resulting in formation of a clot, which narrows the opening of the blood vessel even further.

Doctors found the unexpected cause of vascular diseases

A group of Danish scientists-cardiologists from the University of Copenhagen came to the conclusion that the likelihood of early death from problems with the blood vessels for men is doubled if they lead a solitary existence. The results of their study they presented at the EuroHeartCare Congress in 2018 in Dublin. Many experts believe that loneliness in terms of the risk of such illnesses as coronary heart disease and stroke even more dangerous in its effects than obesity. Danish researchers have added to this conclusion that loneliness can also increase the likelihood of other cardiac disorders such as ischemia, atrial fibrillation. Preliminary research, incidentally, also showed that loneliness can be a factor of premature death. Data showed: people without relatives, family and loved ones often die several years earlier than their peers, sharing your life with someone else. “Loneliness and at the same time affects the health in itself, and leads to the fact that elderly and sick …

Elevated Blood Pressure at Age 50 Tied to Dementia Later

Blood pressure in midlife that was higher than normal — but below the threshold used to treat hypertension in some countries — was linked to increased risk of developing dementia later in life, an analysis of the long-running Whitehall II study found. Men and women who had a systolic blood pressure ≥130 mm Hg at age 50 had a 45% greater risk of developing dementia than people with a lower systolic blood pressure at the same age, reported Archana Singh-Manoux, PhD, of the French National Institute of Health and Medical Research (INSERM) in Paris, and colleagues in European Heart Journal. This association was not seen at ages 60 or 70. “Our analysis suggests that the importance of midlife hypertension on brain health is due to the duration of exposure,” Singh-Manoux said in a statement. “So we see an increased risk for people with raised blood pressure at age 50, but not 60 or 70, because those with hypertension at age 50 are likely to be exposed to this risk for longer.” The American …

5EU Surgical Cardiovascular and Peripheral Vascular Procedures Volumes to 2021

This report presents procedure volumes forecasts for some of the most common cardiovascular and peripheral vascular surgical procedures performed in the five EU countries of France, Germany, Italy, Spain, and the UK (5EU). The forecast period covered by this report is for the years 2016 through 2021. This report also presents an overview of the etiology and epidemiology of selected cardiovascular and peripheral vascular diseases/disorders, prevailing surgical approaches/techniques, and evolving procedural utilization trends. Cardiovascular surgical procedures discussed include cardiac resynchronization therapy, congenital heart defect repair, coronary artery bypass graft surgery, implantation of implantable cardioverter defibrillators, pacemakers, and ventricular-assist devices, heart valve repair/replacement, percutaneous coronary intervention with or without stenting, thrombectomy/thrombolysis, and transmyocardial revascularization. Peripheral vascular interventional/surgical proce…

Buerger’s Disease, a chronic, inflammatory, obstructing tobacco-associated vasculopathy, can lead to tissue loss and major amputations of limbs.

Buerger’s disease is a condition wherein the blood flow to the arteries is restricted due to the constant use of tobacco. Continuous smoking leads to peripheral vascular disease, loss of tissue and in major cases, amputations of the limbs explains vascular surgeon Dr S. Bala Kumar. Buerger’s disease is chronic, inflammatory, obstructing tobacco-associated vasculopathy found in small and medium-sized arteries. It is largely found in young smokers. The flow of blood supply to the arteries and adjacent nerves is affected due to constant use of tobacco products like cigarettes, cigars and beedis. Acute cases of Buerger’s disease result in tissue loss and major amputations of limbs. The incidence in India is between 77 per cent in males and 11 to 23 per cent in females.

The median age of diagnosis is 34 years. This disease is a relatively common cause of peripheral vascular disease in young people and a cause of disability in patients of all ages. It manifests with decreased blood supply in …

Inflammation key to atherosclerosis—but more drug testing needed

Therapies targeting cholesterol and inflammation have both shown the ability to reduce cardiovascular events among patients with atherosclerosis, but more evidence is needed before anti-inflammatory drugs gain widespread use similar to statins, according to a consensus statement published May 14 in the European Journal of Preventive Cardiology. The statement—authored by the European Society of Cardiology’s working group on atherosclerosis and vascular biology—was catalyzed by the results of the recently published CANTOS trial. This study showed the anti-inflammatory drug canakinumab cut the risk of subsequent cardiac events in heart attack survivors, even when LDL cholesterol levels weren’t significantly lowered. “Although the results of the CANTOS trial can be considered a milestone in cardiovascular medicine, canakinumab prescription for patients with cardiovascular risk to improve their prognosis needs to overcome certain hurdles,” wrote the researchers, including lead author Jose…

Medical imaging technology detects vascular disorders, injuries in brain without invasive contrast agents

researchers have developed an analytical imaging technology based on functional MRI for detecting and monitoring cerebral vascular disorders and injuries that does not require the use of contrast agents.
The new imaging method focuses on tracking an intrinsic blood-related MRI signal, which has been shown to travel with the blood. The signal is used as a natural biomarker to assess blood flow in a patient.
“We can compare the signal from symmetric arteries and veins in both hemispheres or neck to assess the cerebrovascular integrity or the balance of blood flow,” said Yunjie Tong, an assistant professor in Purdue’s Weldon School of Biomedical Engineering, who developed the technology along with Blaise Frederick, a biophysicist and associate professor at Harvard Medical School. “The blood flow should be symmetric between the two sides in a healthy subject.”
The time delay between the intrinsic signals from the internal carotid artery and the internal jugular vein represents the cerebr…