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Heart risk calculator due for an update

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Over 11 million Americans are at high risk of having a heart attack or  stroke  in the next 10 years — at least, that’s what the numbers say. The equation doctors use to estimate  cardiovascular  risk is prone to miscalculation, according to a new study, meaning patients may be popping daily aspirin or statins at the wrong dosage. The stakes are higher for African-Americans. With the old equation, 1 in 29 African-Americans may be incorrectly labeled very low or very high risk, according to the study. For example, a 46-year-old black man was estimated to have a 40 percent lower chance of having a heart attack or stroke than a white man of the same age and in identical health. In general, African-Americans are at higher risk of cardiovascular conditions than Caucasians, so miscalculations shouldn’t be taken lightly. The heart risk calculator transforms patient information — age, gender, race,  cholesterol  levels, blood pressure, prescriptions, a...

Outdated equations lead to incorrect prescriptions for cardiovascular conditions

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I recently learned that clinicians in the United States typically calculate this risk using a website or smartphone calculator based on equations approved by the federal government. Those numbers are also built into many electronic health records, so a patient’s risk is automatically calculated during an office visit. But the datasets used to come up with those calculations are decades old — some dating as far back as 70 years. That could leave as many as 11 million Americans at risk of taking the wrong dose of aspirin, statins and blood pressure medications, new research in the  Annals of Internal Medicine  suggests. “A lot has changed in terms of diets, environments and medical treatment since the 1940s,” Stanford primary care physician and  epidemiologist  Sanjay Basu, MD, senior author of the study, said in a Stanford Medicine press release. “So, relying on our grandparents’ data to make our treatment choices is probably not th...

Global Cardiovascular Information System Sales market

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This report on the Global  Cardiovascular  Information System Sales market has been released by Questale with the aim to document the market trends of the Global Cardiovascular Information System Sales market. All key market updates, as well as technological updates, will be enlisted in this report. This report will provide a detailed assessment of majorly on the product overview, sales revenue, main players/suppliers along with the profiles and sales data, and marketing strategy analysis that directly affect the growth rate and revenue of products of Global Cardiovascular Information System Sales market. This report will be a valuable assessment for new startups who wish to enter the Global Cardiovascular Information System Sales market, as it will not just provide the current market trends but also predict the future trends. It will help them to  cautiously  select their genres so that they can have an equal footing to compete with global giants who have an end...

Corindus Vascular Robotics Inc. (DE) (CVRS) Moves Higher on Volume Spike

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Corindus Vascular Robotics Inc. (DE) (CVRS) traded on unusually high volume on Jun. 21, as the stock gained 1.19% to close at $0.77. On the day, Corindus Vascular Robotics Inc. (DE) saw 2.03 million shares trade hands on 6,903 trades. Considering that the stock averages only a daily volume of 1.3 million shares a day over the last month, this represents a pretty significant bump in volume over the norm. Generally speaking, when a stock experiences a sudden spike in trading volume, it may be seen as a bullish signal for investors. An increase in volume means more market awareness for the company, potentially setting up a more meaningful move in stock price. The added volume also provides a level of support and stability for price advances. Corindus Vascular Robotics Inc is engaged in the design, manufacture, and sale of precision vascular robotic-assisted systems for use in interventionalvascular procedures the CorPath System. Its product includes the CorPath 200 and CorPath GRX...

Vitamin D-3 could ‘reverse’ damage to heart

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By probing the effect that vitamin D-3 has on the cells that make up the lining of blood vessels, scientists at Ohio University in Athens, OH, have identified for the first time the role that the “sunshine vitamin” plays in preserving  cardiovascular  health. In a paper published in the International Journal of  Nanomedicine , they describe how they used nanosensors and a cell model to identify the molecular mechanisms that vitamin D-3 can trigger in the  endothelium , which is the thin layer of tissue that lines blood vessels. It was previously believed that the endothelium served no other purpose than to act as an inert “wrapper” of the vascular system, allowing both water and electrolytes to pass in and out of the bloodstream. However, advances over the past 30 years have revealed that the endothelium acts more like an organ that lines the whole of the circulatory system from the “heart to the smallest capillaries,” and who...

Blood transfusion during surgery boosts risk of venous thromboembolism

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Red blood cell (RBC) transfusions during surgery are associated with double the risk of venous  thromboembolism  (VTE) over the ensuing 30 days, researchers reported in JAMA Surgery. Investigators analyzed more than 750,000 patients undergoing surgery from a registry containing 525 North American hospitals. A total of 6.3 percent of the patients received perioperative RBC transfusions, defined as a transfusion from 72 hours before to 72 hours after surgery. These patients experienced VTE at a rate 2.1 times higher than those who didn’t undergo transfusions, even after adjustment for patient characteristics, surgical complexity and hospital length of stay. However, only 0.8 percent of patients in the study experienced postoperative VTE, a combination of  pulmonary  embolism and deep vein thrombosis. “Transfused RBCs have been proposed to modulate the inflammatory cascade,” wrote lead author Ruchika Goel, MD, MPH, with New York Presbyterian Hospital and We...

Peripheral Vascular Disease dangerous for the heart

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Peripheral Vascular Disease is a serious condition that often reveals itself through pain in the legs or other extremities. Often called  Peripheral  Artery Disease or Peripheral  Arterial  Disease (PAD), it is the result of arteriosclerosis or restricted blood flow caused by a buildup of plaque on the inner walls of the  arteries . When the flow of blood is limited, limbs, the heart and brain are  deprived  of the oxygen. Additionally, muscle cells in the wall of the artery overgrow and fat and calcium build up within these irregular spaces. Bleeding into the artery wall can also occur resulting in formation of a clot, which narrows the opening of the blood vessel even further.