Vitamin D-3 could ‘reverse’ damage to heart

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By probing the effect that vitamin D-3 has on the cells that make up the lining of blood vessels, scientists at Ohio University in Athens, OH, have identified for the first time the role that the “sunshine vitamin” plays in preserving cardiovascular health.
In a paper published in the International Journal of Nanomedicine, they describe how they used nanosensors and a cell model to identify the molecular mechanisms that vitamin D-3 can trigger in the endothelium, which is the thin layer of tissue that lines blood vessels.
It was previously believed that the endothelium served no other purpose than to act as an inert “wrapper” of the vascular system, allowing both water and electrolytes to pass in and out of the bloodstream. However, advances over the past 30 years have revealed that the endothelium acts more like an organ that lines the whole of the circulatory system from the “heart to the smallest capillaries,” and whose cells carry out many unique biological functions.
Changes to the endothelium have been linked to several serious health problems, including high blood pressure, insulin resistance, diabetes, tumor growth, virus infections, and atherosclerosis, which is a condition wherein fatty deposits can build up inside arteries and increase the risk of heart attack and stroke.

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